منابع مشابه
ICAP-1 monoubiquitylation coordinates matrix density and rigidity sensing for cell migration through ROCK2-MRCKα balance.
Cell migration is a complex process requiring density and rigidity sensing of the microenvironment to adapt cell migratory speed through focal adhesion and actin cytoskeleton regulation. ICAP-1 (also known as ITGB1BP1), a β1 integrin partner, is essential for ensuring integrin activation cycle and focal adhesion formation. We show that ICAP-1 is monoubiquitylated by Smurf1, preventing ICAP-1 bi...
متن کاملCorrection: ICAP-1 monoubiquitylation coordinates matrix density and rigidity sensing for cell migration through ROCK2-MRCKα balance.
Cell migration is a complex process requiring density and rigidity sensing of the microenvironment to adapt cell migratory speed through focal adhesion and actin cytoskeleton regulation. ICAP-1 (also known as ITGB1BP1), a β1 integrin partner, is essential for ensuring integrin activation cycle and focal adhesion formation. We show that ICAP-1 is monoubiquitylated bySmurf1, preventing ICAP-1bind...
متن کاملCell adaptive response to extracellular matrix density is controlled by ICAP-1–dependent β1-integrin affinity
Cell migration is an integrated process requiring the continuous coordinated assembly and disassembly of adhesion structures. How cells orchestrate adhesion turnover is only partially understood. We provide evidence for a novel mechanistic insight into focal adhesion (FA) dynamics by demonstrating that integrin cytoplasmic domain-associated protein 1 (ICAP-1) slows down FA assembly. Live cell i...
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Although numerous context-aware applications have been developed and there have been technological advances for acquiring contextual information, it is still difficult to develop and prototype interesting context-aware applications. This is largely due to the lack of programming support available to both programmers and end-users. This lack of support closes off the contextaware application des...
متن کاملOptimized Projection Matrix for Compressive Sensing
Compressive sensing (CS) is mainly concerned with low-coherence pairs, since the number of samples needed to recover the signal is proportional to the mutual coherence between projection matrix and sparsifying matrix. Until now, papers on CS always assume the projection matrix to be a random matrix. In this paper, aiming at minimizing the mutual coherence, a method is proposed to optimize the p...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2008
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1802iti1